Whole blood histamine for undermethylation and histamine patterns Plasma zinc, serum copper, and ceruloplasmin for copper-zinc imbalance and free copper patterns Urinary pyrroles / HPL for pyroluria and zinc/B6 depletion patterns Homocysteine, SAM, SAH, and SAM/SAH ratio when methylation efficiency needs clarification Vitamin D, CBC, CMP, B12, folate, glucose, and inflammatory markers for general metabolic context Organic acids, gut, mold, or toxic burden testing when history suggests oxidative stress or environmental load How these mechanisms integrate within the Walsh Approach OCD symptoms often arise from a biochemical constellation rather than one isolated neurotransmitter defect
10.1016/j.joca.2003.09.016 23 BurrD
In the Nutrients paper, reference is made to a number of studies of healthy individuals, wherein glutathione stores improved following whey protein supplementation, since whey has a higher cysteine content
Glutathione in the Nervous System as a Potential Therapeutic Target to Control the Development and Progression of Amyotrophic Lateral Sclerosis Chatterjee, A